Bioscience

Researchers find oncogene is important in pancreatic cancer growth and spread

February 23, 2010

By Flinn Foundation

[ScienceDaily] – Researchers at the Mayo Clinic campus in Florida have found that PKC-iota (PKCi), an oncogene important in colon and lung cancers, is over-produced in pancreatic cancer and is linked to poor patient survival. They also found that genetically inhibiting PKCi in laboratory animals led to a significant decrease in pancreatic tumor growth and spread.

The discovery, reported in the March 1 issue of Cancer Research, is especially encouraging, they say, because an experimental agent that targets PKCi is already being tested in patients at Mayo Clinic.

For more information: Researchers Find Oncogene Is Important in Pancreatic Cancer Growth and Spread